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Our main objective here at Farrow's Country Collies, aside from temperment & standard, is to provide potential buyers with puppies from a well managed breeding program of Rough Collies. We have genetically tested for common issues known to affect the breed. These test are collected by a buccal (cheek) or blood swab and are 100% accurate. 

For better understanding of inheritance we have prepared a short explanation of the three (3) most common, but different modes of inheritance:

 
  • A litter whose parents are clear (n/n=negative/negative) will also be clear (n/n), as a puppy can NEVER inherit a gene that a parent does not have to offer.
 
  • A litter who has one (1) parent that is clear (n/n=negative/negative) and one (1) parent that is a carrier (n/p=negative/positive) declares each puppy within the litter has a 50/50 chance of having the positive gene passed onto them. 
 
  • A litter whose parents are affected (p/p=positive/positive) are also affected, as an affected parent only has an affected gene to offer. ***Farrow's Country Collies will not breed any dog who is "Affected!"***

All of Farrow's Country Collies genetic testing is done through the following laboratories:  

 
Below is a list along with a brief explanation of the genetic testing that is completed for each Collie here at Farrow's Country Collies.
 
  • PRA-RCD2 or "Collie PRA" (rod-cone dysplasia type 2)(rcd2), is a form of retinal degeneration that is an abnormal development of the rods and cones leading to an early onset of night blindness. Collie PRA/rcd2 is inherited in an automosmal recessive manner. In order for disease to occur two (2) copies of mutation must be present. Carriers do not show the gene, but are able to pass the gene on to half of their offspring. http://www.optigen.com/opt9_rcd2testpage.html
  • Collie Eye Anomaly (CEA), is a inherited bilaterial eye disease causing abnormal development in layers of tissue in the eye under the retina called the choroid. These changes cause what is referred to as Choroidal Hypoplasia. CEA can be managed as n/n (Clear) is a stable gene to be bred to a CEA/n (Carrier) and a CEA/CEA (Affected) dog. This removes the risk of producing affected puppies. http://www.pawprintgenetics.com/products/tests/details/92/?breed=42
  • Degenerative Myelopathy (DM), is a progressive neurological disorder that affects the spinal cord of dogs. DM can be managed by breeding a n/n (Clear: will not pass gene) which is a stable gene to a DM/n (Carrier: could pass on either the mutant or clear gene to 50% of the offspring) and a DM/DM (Affected: 2 copies of mutant gene.) This cross removes the risk of producing affected puppies as only one (1) parent has a mutation to pass. http://www.pawprintgenetics.com/products/tests/details/87/?breed=42
  • Multi-Drug Resistance Gene (MDR1) means Ivermectrin, Loperamide, and a number of other drugs should not be administered to a dog who is a Carrier of the mutation gene or one who is affected (2 copies of mutant gene.) One (1) in two (2) Collies have at least one (1) copy of the gene. N/N (Clear) dog will not pass on the defective gene to puppies, Mut/Wt (Carrier)  both the clear & mutant gene were detected. Some sensitivity can occur, puppies will have a 50/50 chance of having the defective gene passed onto them. Mut/Mut (Affected), the dog carrries two (2) copies of the mutant gene and will react to Ivermectrin and other drugs as well as pass a copy of the gene to offspring. http://www.pawprintgenetics.com/products/tests/details/93/?breed=42

 
Valuable information pertaining to the Collie breed in relation to dogs who are carriers or affected by the MDR1 gene mu
Valuable information pertaining to the Collie breed in relation to dogs who are carriers or affected by the MDR1 gene mutation.